Kev lag luam tshuaj lom neeg zoo yog kev lag luam ntawm kev tsim cov tshuaj zoo hauv kev lag luam chemical, uas txawv ntawm cov khoom siv tshuaj lom neeg lossis cov tshuaj bulk.Fine chemical kev lag luam yog ib qho ntawm cov cim tseem ceeb ntawm ib lub teb chaws cov txheej txheem kev lag luam.Nws cov yam ntxwv yooj yim yog tsim cov khoom muaj txiaj ntsig zoo, ntau yam, cov khoom lag luam zoo nkauj rau kev lag luam hauv ntiaj teb thiab cov neeg muaj txiaj ntsig zoo nkauj thiab muaj nuj nqis. qee lub teb chaws tsim kev lag luam tau ua tiav qhov kev hloov pauv ntawm kev lag luam tshuaj lom neeg txoj kev loj hlob mus rau kev lag luam tshuaj zoo, thiab kev ua kom zoo ntawm kev lag luam tshuaj lom neeg tau dhau los ua kev lag luam thoob ntiaj teb.Fine tshuaj muaj xws li tshuaj tua kab, tshuaj, dyes (pigments), thiab lwm yam. Cov tshuaj tshwj xeeb muaj xws li pub additives, zaub mov additives, adhesives, surfactants, dej kho chemicals, tawv chemicals, oilfield chemicals, electronics chemicals, papermaking chemicals thiab lwm yam ntau tshaj 50 teb.

Pharmaceutical intermediates xa mus rau cov tshuaj nruab nrab uas ua rau hauv cov txheej txheem ntawm cov tshuaj synthesis thiab yog cov khoom siv tshuaj zoo.Pharmaceutical intermediates tuaj yeem muab faib ua cov tshuaj tua kab mob intermediates, antipyretic thiab analgesic intermediates, plawv plawv intermediates, thiab anticancer intermediates raws li lawv daim ntawv thov kev lag luam. ntawm cov kws tshuaj intermediates yog cov tshuaj raw khoom siv hauv kev lag luam, thaum kev lag luam downstream yog cov tshuaj API thiab kev lag luam kev npaj.Raws li cov khoom lag luam loj, tus nqi ntawm cov khoom siv tshuaj lom neeg yooj yim hloov pauv tau zoo heev, uas cuam tshuam ncaj qha rau cov nqi tsim khoom lag luam. Pharmaceutical intermediates thiab subdivided rau hauv thawj theem nrab thiab qib siab intermediates, thawj qhov nruab nrab vim qhov nyuaj ntawm kev siv tshuab tsis yog siab, tus nqi qis, thiab tus nqi ntxiv nyob rau hauv cov khoom siv oversupply, advanced intermediates yog thawj cov tshuaj tiv thaiv nruab nrab cov khoom, piv nrog cov primary intermediate, complex qauv, tsuas yog ib los yog ob peb kauj ruam mus rau kev npaj cov khoom muaj nqis ntxiv downstream, nws tag nrho cov margin theem siab tshaj cov intermediates kev lag luam gross margin.Raws li cov thawj intermediate lwm tus neeg yuav tsuas muab yooj yim intermediate ntau lawm, lawv yog nyob rau hauv pem hauv ntej kawg ntawm cov kev lag luam saw nrog qhov loj tshaj kev sib tw siab thiab tus nqi siab, thiab tus nqi hloov pauv ntawm cov ntaub ntawv raw cov ntaub ntawv muaj kev cuam tshuam zoo rau lawv.Senior intermediate cov neeg muag khoom, ntawm qhov tod tes, tsis tsuas yog muaj kev sib txuas lus muaj zog tshaj junior. cov chaw muag khoom, tab sis qhov tseem ceeb tshaj, lawv dais cov khoom lag luam ntawm cov khoom nruab nrab nrog cov ntsiab lus siab thiab ua kom muaj kev sib raug zoo nrog ntau lub tuam txhab, yog li tus nqi hloov pauv ntawm cov khoom siv raw khoom muaj kev cuam tshuam tsawg dua rau lawv.Non-gmp intermediates thiab GMP intermediates tuaj yeem raug cais raws li. qib ntawm kev cuam tshuam rau qhov kawg API zoo.Non-gmp intermediate yog hais txog cov kws tshuaj intermediate before tus API pib cov khoom; GMP intermediate yog hais txog cov tshuaj intermediate tsim nyob rau hauv cov kev cai ntawm GMP, uas yog, ib yam khoom uas yog tsim tom qab ib tug API pib cov ntaub ntawv, thaum lub sij hawm API synthesis cov kauj ruam, thiab uas undergoes ntxiv molecular hloov los yog refinement ua ntej ua ib API.

Qhov thib ob patent pob zeb ncov yuav txuas ntxiv txhawb qhov kev thov rau cov khoom nruab nrab nruab nrab
Kev lag luam tshuaj intermediate fluctuates nyob rau hauv tus ntawm lub zuag qhia tag nrho xav tau ntawm downstream kws lag luam, thiab nws periodicity yeej ib txwm ua raws li cov kev lag luam kws tshuaj.Cov influences yuav muab faib ua lwm yam tseem ceeb thiab sab hauv: lwm yam tseem ceeb yog xa mus rau kev pom zoo. Lub voj voog ntawm cov tshuaj tshiab hauv kev ua lag luam; Cov yam ntxwv sab hauv feem ntau yog xa mus rau patent tiv thaiv lub voj voog ntawm cov tshuaj tshiab.Qhov kev pom zoo ntawm cov tshuaj tshiab los ntawm cov koom haum tswj hwm tshuaj xws li FDA kuj muaj qee yam cuam tshuam rau kev lag luam.Thaum lub sij hawm ncua sij hawm ntawm kev pom zoo tshuaj tshiab thiab tus naj npawb ntawm cov tshuaj tshiab tau pom zoo rau cov tuam txhab tshuaj, qhov kev thov rau cov kev pab cuam kws kho mob yuav raug tsim tawm.Raws li tus naj npawb ntawm cov tshuaj tshiab tshuaj thiab cov tshuaj lom neeg tshiab tau pom zoo los ntawm THE FDA nyob rau hauv Xyoo kaum xyoo dhau los, ntau qhov kev pom zoo tshuaj tshiab yuav ua rau muaj kev xav tau rau cov khoom nruab nrab nruab nrab, yog li txhawb kev lag luam kom muaj kev loj hlob zoo.Thaum qhov kev tiv thaiv patent ntawm cov tshuaj tshiab tas sij hawm, cov tshuaj generic yuav zoo heev, thiab cov tuam txhab nruab nrab yuav tseem txaus siab rau qhov kev loj hlob tawg ntawm kev thov hauv lub sijhawm luv luv.Raws li Kev Ntsuam Xyuas cov txheeb cais, nws kwv yees tias txij xyoo 2017 txog 2022, yuav muaj 194 billion yuan ntawm kev lag luam tshuaj uas ntsib qhov teeb meem ntawm patent tas sij hawm, uas yog qhov thib ob patent pob zeb ncov txij li xyoo 2012.

Ariations nyob rau hauv xyoo tas los no, nrog rau kev nthuav dav thiab cov qauv tshuaj nyuaj, kev tshawb fawb tshuaj tshiab thiab kev txhim kho kev ua tau zoo yog txo, qhov nce sai ntawm kev tshawb fawb tshuaj tshiab thiab kev tsim kho cov nqi ntawm McKinsey hauv Nat.Rev. DrugDiscov."hais, hauv 2006-2011, kev tshawb fawb tshuaj tshiab thiab kev txhim kho kev vam meej tsuas yog 7.5%, txij xyoo 2012 txog 2014, vim yog cov macromolecules lom neeg xaiv tau zoo thiab tsis muaj toxicity ntawm kev ncua deb (tshuaj nyob rau hauv lub lig txoj kev loj hlob theem, uas yog, los ntawm 2006-2011). qhov chaw kho mob theem III rau cov npe tau pom zoo muaj 74% kev ua tiav), kev tshawb fawb tshuaj thiab kev txhim kho tag nrho cov kev vam meej ntawm kev nce me ntsis, tab sis tseem nyuaj rau rov qab mus rau 16.40% kev vam meej hauv 90 s.Tus nqi ntawm kev ua tiav cov npe tshiab tshuaj tau nce los ntawm peb $ 1.188 nphom hauv 2010 rau peb $ 2.18 nphom hauv 2018, ze li ob npaug.Lub caij no, tus nqi rov qab los ntawm cov tshuaj tshiab tseem poob qis.Hauv 2018, lub ntiaj teb TOP12 kws tshuaj loj tsuas yog ua tus nqi rov qab ntawm 1.9% ntawm kev nqis peev hauv kev tshawb fawb thiab kev loj hlob.

Kev nce nqi r & d thiab poob rov qab los ntawm r&d peev tau ua rau muaj kev kub ntxhov rau cov tuam txhab tshuaj, yog li lawv yuav xaiv outsource cov txheej txheem tsim khoom rau CMO cov lag luam yav tom ntej los txo cov nqi.Raws li ChemicalWeekly, cov txheej txheem ntau lawm suav txog li 30% ntawm tag nrho cov nqi ntawm cov tshuaj thawj.CMO/CDMO qauv tuaj yeem pab cov tuam txhab tshuaj txo tus nqi tag nrho ntawm cov khoom vaj khoom tsev ruaj khov, kev ua haujlwm zoo, tib neeg cov peev txheej, ntawv pov thawj, kev tshuaj xyuas thiab lwm yam. los ntawm 12-15% Tsis tas li ntawd, ADOPTION ntawm CMO / CDMO hom tuaj yeem pab cov tuam txhab tshuaj los txhim kho cov tshuaj tiv thaiv tawm los, ua kom lub voj voog luv thiab ua kom muaj kev nyab xeeb, uas tuaj yeem txuag lub sijhawm ntawm kev tsim khoom, txo lub voj voog r & d. Cov tshuaj tshiab, ua kom nrawm nrawm ntawm kev lag luam tshuaj, thiab ua kom cov tuam txhab lag luam tau txais txiaj ntsig ntau dua patent.

Suav CMO cov tuam txhab muaj qhov zoo xws li tus nqi qis ntawm cov khoom siv raw thiab kev ua haujlwm, cov txheej txheem hloov pauv thiab thev naus laus zis, thiab lwm yam, thiab kev hloov pauv ntawm kev lag luam thoob ntiaj teb CMO mus rau Tuam Tshoj txhawb kev nthuav dav ntxiv ntawm Tuam Tshoj CMO kev lag luam sib koom.Lub ntiaj teb CMO / CDMO kev lag luam yuav tsum kom tshaj peb $ 102.5 nphom hauv 2021, nrog rau kev loj hlob ntawm kwv yees li 12.73% hauv 2017-2021, raws li South qhov kev kwv yees.

Nyob rau hauv lub ntiaj teb no zoo tshuaj ua lag luam nyob rau hauv 2014, kws tshuaj thiab nws intermediates, tshuaj tua kab thiab nws intermediates yog lub sab saum toj ob sub-industries ntawm zoo tshuaj kev lag luam, accounting rau 69% thiab 10% raws li.Tuam Tshoj muaj ib tug muaj zog petrochemical kev lag luam thiab ib tug loj tus naj npawb ntawm cov tshuaj. chemical raw khoom manufacturers, uas tau tsim muaj pawg, ua ntau ntau yam ntawm raw thiab auxiliary cov ntaub ntawv uas yuav tsum tau rau zus tau tej cov high-qib zoo tshuaj muaj nyob rau hauv Suav teb, txhim kho efficiency thiab txo tag nrho cov nqi.Tam sim no, Tuam Tshoj muaj ib tug kuj. ua tiav cov txheej txheem kev lag luam, uas ua rau tus nqi ntawm cov khoom siv tshuaj lom neeg, kev tsim kho thiab kev teeb tsa hauv Suav teb qis dua li ntawm cov teb chaws tsim lossis txawm tias feem ntau cov teb chaws tsim, yog li txo kev nqis peev thiab cov nqi tsim khoom. Tsis tas li ntawd, Tuam Tshoj muaj ntau lub peev xwm thiab qis- tus nqi tshuaj engineers thiab cov neeg ua haujlwm muaj.Intermediates kev lag luam hauv Suav teb tau tsim los ntawm kev tshawb fawb thiab kev loj hlob mus rau production thiab kev muag khoom ntawm ib qho kev ua tiav ntawm cov txheej txheem ua tiav, kev tsim tshuaj ntawm cov ntaub ntawv raw cov ntaub ntawv thiab cov khoom nruab nrab rau kev yooj yim tuaj yeem tsim cov txheej txheem tiav, tsuas yog qee qhov yuav tsum tau import, tuaj yeem tsim cov tshuaj intermediates, tshuaj tua kab intermediates thiab lwm yam 36 pawg loj, ntau dua. 40000 hom intermediates, muaj ntau yam khoom nruab nrab ua tiav ib tug loj tus naj npawb ntawm exports, intermediate exports ntawm ntau tshaj 5 lab tons ib xyoos twg, tau ua lub ntiaj teb no tus loj tshaj plaws intermediates ntau lawm thiab exporter.

Tuam Tshoj cov kws tshuaj intermediates kev lag luam tau tsim muaj txij li xyoo 2000.Thaum lub sijhawm ntawd, cov tuam txhab tshuaj hauv cov teb chaws tsim tau them nyiaj ntau dua rau kev tshawb fawb thiab kev tsim kho thiab kev lag luam kev lag luam raws li lawv cov kev sib tw tseem ceeb thiab ua kom nrawm rau kev hloov pauv ntawm cov tshuaj intermediates thiab cov tshuaj nquag synthesis rau cov teb chaws tsim. nrog cov nqi qis dua.Yog li ntawd, Tuam Tshoj txoj kev lag luam kws tshuaj intermediates tau siv lub sijhawm no kom tau txais kev txhim kho zoo heev.Tom qab ntau tshaj kaum xyoo ntawm kev txhim kho ruaj khov, Tuam Tshoj tau dhau los ua ib qho tseem ceeb hauv nruab nrab ntau lawm hauv lub ntiaj teb kev faib ua haujlwm hauv kev lag luam tshuaj nrog kev txhawb nqa ntawm Lub teb chaws tag nrho cov kev cai thiab ntau yam kev cai.Los ntawm 2012 mus rau 2018, cov zis ntawm Tuam Tshoj tus kws tshuaj intermediates kev lag luam tau nce los ntawm kwv yees li 8.1 lab tons nrog ib tug lag luam loj ntawm li 168.8 billion yuan mus txog 10.12 lab tons nrog ib tug lag luam loj ntawm 2017 billion yuan.Tuam Tshoj cov kws tshuaj. nruab nrab industry tau ua tiav qhov kev sib tw muaj zog hauv kev ua lag luam, thiab txawm tias qee tus neeg tsim khoom nruab nrab tau tsim cov intermediates nrog cov qauv molecular complex thiab cov kev cai siab.Ib tug loj tus naj npawb ntawm cov khoom lag luam tau pib ua lag luam thoob ntiaj teb.Txawm li cas los xij, ntawm tag nrho, Tuam Tshoj txoj kev lag luam nruab nrab tseem nyob rau lub sijhawm tsim khoom ntawm cov qauv kev ua kom zoo dua qub thiab kho dua tshiab, thiab qib thev naus laus zis tseem qis dua.Feem ntau ntawm cov khoom hauv kev lag luam kws tshuaj intermediates tseem yog thawj kws tshuaj intermediates, thaum muaj coob tus kws kho mob siab heev intermediates thiab txhawb intermediates ntawm cov tshuaj tshiab patented yog tsawg.