2,4-Difluoroaniline

CAS367-25-9

Cov khoom siv tshuaj lom neeg: cov roj daj daj.

Siv: 2,4-Difluoroaniline yog ib qho tshuaj nruab nrab hauv kev tsim cov organic. Hauv kev lag luam tshuaj, nws yog siv rau hauv kev tsim cov difluorophenylsalicylic acid thiab polyfluorodiphenyl acid. Difluorophenylsalicylic acid yog ib qho tshuaj carboxylic acid nonsteroidal anti-inflammatory drug (NSAID), nrog lub npe thoob ntiaj teb tsis muaj npe (INN) Diflunisal. Cov tshuaj tshiab no ntawm salicylic acid, thaum tsis muaj pawg acetyl ntawm aspirin, muaj ib pawg difluorophenyl, ua rau muaj tsawg dua cov kev phiv tshuaj antiplatelet, cov tshuaj tiv thaiv plab hnyuv me dua, thiab lub sijhawm ua haujlwm ntev li 8-12 teev. Nws yuav yog cov tshuaj salicylic acid zoo tshaj plaws. Nws kuj yog ib qho tshuaj nruab nrab tseem ceeb hauv kev tsim tshuaj tua kab.

Cov mis mos molecular C6H5F2N,

qhov hnyav molecular 129.11,

Tus lej EINECS 206-687-5

Melting point -7.5 °C (lit.)

Kub taw tes 170 °C/753 mmHg (lit.)

Qhov Ceev 1.268 g/mL ntawm 25 °C (lit.)

Refractive index n20/D 1.506 (lit.)

Qhov kub hnyiab 145 °F

Txoj Kev Tsim Khoom 1. Txoj Kev Txo 2,4-Difluoronitrobenzene: Hmoov hlau thiab ammonium chloride aqueous kua raug ntxiv rau hauv lub reactor txo qis, cua sov rau reflux, thiab tom qab ntawd 2,4-difluoronitrobenzene raug ntxiv rau hauv qab. Tom qab ntxiv tiav lawm, reflux rau 2 teev. Tom qab qhov kev tshuaj tiv thaiv tiav lawm, cov khoom yog chav distilled, sib cais los ntawm Chemicalbook, thiab ziab nrog calcium chloride kom tau txais cov khoom tsim nyog nrog cov txiaj ntsig ntawm 87%. 2. Tau txais los ntawm 1,2,4-trichlorobenzene los ntawm nitration, fluorination, thiab reductive dechlorination; lossis tau txais los ntawm m-phenylenediamine los ntawm diazotization, hloov pauv, nitration, thiab txo qis.

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