Cov Lus Txhais: Benzene, 2,4-dichloro-1-methyl-; Toluene, 2,4-dichloro-; 2,4-dichloro-1-methylbenzene; 2,4-DCT; 2,4-DICHLOROTOLUENE; 2,4-DICHLOROMETHYLBENZENE; 1,3-DICHLORO-4-METHYLBENZENE; 2,4-dichloro-1-methyl-benzene

Tus lej CAS: 95-73-8
Cov mis mos molecular: C7H6Cl2
Qhov hnyav molecular: 161.03
Tus lej EINECS: 202-445-8

Pawg sib xws:Cov khoom lag luam ua liaj ua teb thiab ib puag ncig tus qauv; triazole fungicides; fungicide intermediates; tshuaj tua kab intermediates; cov khoom siv raw organic; intermediates; organic intermediates; Organics; Aryl; C7; Halogenated Hydrocarbons; Aromatics; Building Blocks; Chemicalbook Chemical Synthesis; Hydrogenated Hydrocarbons; OrganicBuildingBlocks; Analytical standard products; Organic building blocks; Pesticidesintermediate; Halogenated hydrocarbons; Organic chemical raw materials.

2,4-Dichlorotoluene siv thiab txoj kev tsim cov khoom
Cov khoom siv tshuaj lom neeg: tsis muaj xim thiab pob tshab.
Siv:
1) Siv ua cov tshuaj tua kab, cov xim thiab cov tshuaj, siv rau hauv kev tsim cov tshuaj 2,4-dichlorobenzaldehyde, cov tshuaj xws li adipine, buprofen, thiab lwm yam.
2) 2,4-Dichlorotoluene yog ib qho nruab nrab ntawm cov kab mob bactericides diniconazole thiab benzylchlorotriazole, thiab Chemicalbook kuj yog cov khoom siv raw rau kev npaj ntawm 2,4-dichlorobenzaldehyde.
3) Cov khoom siv raw organic synthetic, siv rau hauv kev lag luam tshuaj rau kev tsim cov tshuaj antimalarial, Adepine, thiab kev tsim cov kua qaub ventral. Siv rau hauv cov tshuaj tua kab intermediates los tsim 2,4-dichlorobenzyl chloride, 2,4-dichlorobenzoyl chloride, thiab 2,4-dichlorobenzoic acid.

Muaj ob txoj kev tsim khoom siv hluavtaws.
1. Txoj kev 1.2,4-dichlorotoluene siv 2,4-diaminotoluene ua cov khoom siv raw, thiab tau los ntawm diazotization thiab chlorination. Muab hydrochloric acid thiab dej rau hauv lub lauj kaub tshuaj tiv thaiv, cua sov rau 50 ℃, yaj 2,4-diaminotoluene hauv qab do, tom qab ntawd muab hydrochloric acid thiab cuprous chloride rau hauv lub lauj kaub, ntxiv 1% sodium nitrite kua sib npaug rau hauv Chemicalbook, Qhov kub yog khaws cia ntawm kwv yees li 60 ℃, sawv ntsug rau txheej, cov khoom nyoos qis dua yog ntxuav nrog dej kom txog thaum nws yog nruab nrab, alkali yog ntxiv rau alkali, thiab tom qab ntawd ntxuav nrog dej kom tshem tawm alkali, cov nyoos 2,4-dichlorotoluene yog sib cais, thiab cov khoom tiav yog chav distilled. . Txoj kev 2.3-chloro-4-toluidine yog tau los ntawm diazotization tshuaj tiv thaiv nrog sodium nitrite, thiab Sandmeyer tshuaj tiv thaiv nrog tooj liab chloride.

2.Txoj kev tsim khoom thiab nws cov txheej txheem npaj yog raws li nram no. Hauv txoj kev parachlorotoluene, p-chlorotoluene thiab catalyst ZrCl4 raug muab tso rau hauv lub reactor, thiab cov pa chlorine raug tso tawm kom ua tiav cov tshuaj chlorination. Tus nqi ntawm cov pa chlorine raug tswj kom txog thaum kawg ntawm cov tshuaj tiv thaiv thiab cov tshuaj tiv thaiv raug nres. Cov tshuaj reactant tau txais muaj 85.1% ntawm 2,4-dichlorotoluene. Yog tias FeCl3 raug siv ua catalyst los ua tiav cov tshuaj chlorination ntawm 10 ~ 15 ℃ kom txog thaum qhov ceev ntawm cov tshuaj yog 1.025, cov khoom muaj 2,4-dichlorotoluene thiab 3,4-dichlorotoluene, thiab qhov sib piv ntawm ob lub Cheebtsam yog 100:30. Tom qab chlorination tiav, ntxuav nrog dej kom tsis muaj zog, thiab kho nrog 10% NaOH kua ntawm 100 ~ 110 ℃ kom tshem tawm lwm yam impurities. Cov chloride kho tau raug kho thiab sib cais hauv lub pej thuam kho kom zoo (2,4-dichloro Toluene bp200 ° C, 3,4-dichlorotoluene bp207 ° C). Cov txiaj ntsig ntawm 2,4-dichlorotoluene thiab 3,4-dichlorotoluene yog 64.4% thiab 19.8%, feem. Txoj kev Ortho-chlorotoluene o-chlorotoluene siv sulfuryl chloride ua tus neeg sawv cev chlorinating los ua cov tshuaj tiv thaiv chlorination ntawm 142 ～ 196 ℃. Cov khoom yog 2,4-dichlorotoluene thiab 2,3-dichlorotoluene, thiab tsis muaj tshuaj lom Cov khoom xyaw ntawm cov khoom siv raw yog 55%, 6%, thiab 39%, feem. Tom qab distillation (2,4-dichlorotoluene bp 200 ° C, 2,3-dichlorotoluene bp 207-208 ° C, o-chlorotoluene bp 157-159 ° C), 2,4-dichlorotoluene tau sib cais. Txoj kev Ortho-nitrotoluene Ortho-nitrotoluene yog chlorinated nyob rau hauv lub xub ntiag ntawm FeCl3 catalyst ntawm 35 ～ 40 ℃. Thaum qhov ceev ntawm cov tshuaj reactant ncav cuag 1.320 (15 ℃), ntxuav cov khoom kom tsis muaj zog, thiab cov tshuaj reactant muaj 15% ntawm cov khoom siv raw, 2-chloro-6-nitrotoluene 49%, 4-chloro-2-nitrotoluene 21%, thiab 15% polychloride, tom qab kev kho thiab kev kho crystallization, phau ntawv Chemicalbook rau 2-chloro-6-nitrotoluene Cov txiaj ntsig ntawm 4-chloro-2-nitrotoluene thiab 4-chloro-2-nitrotoluene yog 50% thiab 30% feem. 4-chloro-2-nitrotoluene tau txais los ntawm kev txo qis hydrogenation thiab kev sib xyaw ua pa kom tau txais 4-chloro-2-amino. Toluene, diazotization thiab ntxiv CH2Cl2 rau Sandmeyer tshuaj tiv thaiv kom tau txais 2,4-dichlorotoluene. Txoj kev no siv los tsim 4-chloro-2-nitrotoluene uas yog cov khoom lag luam ntawm 2-chloro-6-nitrotoluene (siv ua ib qho nruab nrab ntawm cov tshuaj tua kab quinclorac). Txoj Kev 2,4-Diaminotoluene 2,4-Diaminotoluene dhau los ntawm kev sib xyaw diazotization nyob rau hauv qhov muaj NaNO2 thiab hydrochloric acid, thiab tom qab ntawd ua Sandmeyer kev sib xyaw nyob rau hauv qhov muaj Cu2Cl2 kom tau txais 2,4-dichlorotoluene. Txoj Kev 3-Chloro-4-methylaniline 3-chloro-4-methylaniline thiab hydrochloric acid raug ntxiv rau hauv lub lauj kaub tshuaj tiv thaiv, NaNO2 cov kua dej raug ntxiv rau ntawm 3 ~ 5 ℃, thiab qhov ntxiv tau ua tiav hauv 2 ~ 3 teev rau diazotization Tom qab kev sib xyaw, cov kua diazotized raug ntxiv rau ntawm cov kua hydrochloric acid uas muaj Cu2Cl2 ntawm 2-5 ° C kom ua Sandmeyer kev sib xyaw kom tau txais 2,4-dichlorotoluene. Ntawm cov txheej txheem saum toj no, cov chloride tsim los ntawm kev siv p-chlorotoluene thiab o-chlorotoluene ua cov khoom siv raw muaj ntau yam tsis huv thiab muaj cov ntsiab lus kub zoo sib xws. Nws yog qhov tsim nyog siv cov tsev kho kom zoo kom ua tiav ntau dua 98% ntawm 2,4-dichlorotoluene. Ob txoj kev no nyuaj rau kev ua haujlwm, thiab cov nqi peev khoom siv siab. Txoj kev 2,4-diaminotoluene tsis haum rau kev lag luam, thiab txoj kev o-nitrotoluene thiab txoj kev 3-chloro-4-methylaniline los npaj 2,4-dichlorotoluene muaj cov hauv paus ntsiab lus zoo ib yam, thiab ob qho tib si xav tau diazotization thiab Sandmeyer Hauv kev teb, muaj qhov tsis txaus ntawm cov dej khib nyiab ntau dua. Txoj kev o-nitrotoluene siv los tsim 2-chloro-6-nitrotoluene, uas raug txo kom tau 2-chloro-6-aminotoluene, uas yog ib qho tseem ceeb rau kev tsim cov tshuaj tua kab quinclorac.