Cov ntsiab lus: Benzene, 2,4-dichloro-1-methyl-; Toluene, 2,4-dichloro-; 2,4-dichloro-1-methylbenzene; 2,4-DCT; 2,4-DICHLOROTOLUENE; 2,4- 1,3-DICHLORO-4-METHYLBENZENE; 2,4-dichloro-1-methyl-benzene

CAS Nr .: 95-73-8
Cov mis mos molecular: C7H6Cl2
Molecular Luj: 161.03
PIB: 202-445-8

Yam muaj feem:Agricultural thiab ib puag ncig tus qauv khoom; triazole fungicides; fungicide intermediates; tshuaj tua kab intermediates; organic raw khoom; nruab nrab; organic intermediates; Organics; Aryl; C7; Halogenated Hydrocarbons; Aromatics; Tsev Blocks; Chemicalbook Chemical Synthesis; Hydrogenated Hydrocarbons; OrganicBuildingBlocks; Analytical standard products; Organic building blocks; Pesticides intermediate; Halogenated hydrocarbons; Organic chemical raw khoom.

2,4-Dichlorotoluene siv thiab synthesis txoj kev
Chemical zog: tsis muaj xim thiab pob tshab kua.
Siv:
1) Siv los ua cov tshuaj tua kab nruab nrab, dyes thiab tshuaj, siv hauv kev tsim cov 2,4-dichlorobenzaldehyde, tshuaj xws li adipine, buprofen, thiab lwm yam.
2) 2,4-Dichlorotoluene yog ib qho nruab nrab ntawm cov bactericides diniconazole thiab benzylchlorotriazole, thiab Chemicalbook kuj yog cov khoom siv raw rau kev npaj ntawm 2,4-dichlorobenzaldehyde.
3) Organic hluavtaws raw cov ntaub ntawv, siv nyob rau hauv kev lag luam kws tshuaj rau zus tau tej cov tshuaj antimalarial, Adepine, thiab cov synthesis ntawm ventral acid. Siv cov tshuaj tua kab nruab nrab los tsim 2,4-dichlorobenzyl chloride, 2,4-dichlorobenzoyl chloride, thiab 2,4-dichlorobenzoic acid.

Muaj ob txoj kev siv hluavtaws rau txoj kev tsim khoom.
1. Txoj kev 1.2,4-dichlorotoluene siv 2,4-diaminotoluene ua raw khoom, thiab tau los ntawm diazotization thiab chlorination. Muab hydrochloric acid thiab dej tso rau hauv lub lauj kaub cov tshuaj tiv thaiv, kub rau 50 ℃, yaj 2,4-diaminotoluene nyob rau hauv nplawm, ces muab hydrochloric acid thiab cuprous chloride rau hauv lub lauj kaub, ntxiv 1% sodium nitrite tov tusyees rau hauv Chemicalbook, qhov kub thiab txias yog tswj ntawm Txog 60 ℃, sawv ntsug rau txheej txheej, cov khoom siv qis qis yog ntxuav nrog dej kom txog thaum nruab nrab, alkali ntxiv rau alkali, thiab tom qab ntawd ntxuav nrog dej kom tshem tawm cov alkali, cov crude 2,4-dichlorotoluene sib cais, thiab cov Cov khoom tiav yog chav distilled. . Txoj kev 2.3-chloro-4-toluidine yog tau los ntawm diazotization cov tshuaj tiv thaiv nrog sodium nitrite, thiab Sandmeyer cov tshuaj tiv thaiv nrog tooj liab chloride.

2.Cov txheej txheem ntau lawm thiab nws txoj kev npaj yog raws li hauv qab no. Nyob rau hauv txoj kev parachlorotoluene, p-chlorotoluene thiab catalyst ZrCl4 tau muab tso rau hauv lub reactor, thiab cov roj chlorine yog vented los nqa tawm cov tshuaj chlorination. Tus nqi ntawm cov tshuaj chlorine yog tswj kom kawg ntawm cov tshuaj tiv thaiv thiab cov tshuaj tiv thaiv raug tso tseg. Cov reactant tau muaj 85.1% ntawm 2,4-dichlorotoluene. Yog hais tias FeCl3 yog siv los ua tus catalyst los ua cov tshuaj chlorination ntawm 10 ~ 15 ℃ kom txog rau thaum cov txheeb ze ntom ntom ntawm cov tshuaj yog 1.025, cov khoom muaj 2,4-dichlorotoluene thiab 3,4-dichlorotoluene, thiab qhov sib piv loj ntawm ob. Cheebtsam yog 100:30. Tom qab cov tshuaj chlorination tiav lawm, ntxuav nrog dej kom nruab nrab, thiab kho nrog 10% NaOH tov ntawm 100 ~ 110 ℃ kom tshem tawm lwm yam impurities. Cov tshuaj chloride kho tau raug kho thiab sib cais nyob rau hauv lub tshuab ua kom muaj txiaj ntsig zoo (2,4-dichloro Toluene bp200 ° C, 3,4-dichlorotoluene bp207 ° C). Cov txiaj ntsig ntawm 2,4-dichlorotoluene thiab 3,4-dichlorotoluene yog 64.4% thiab 19.8%, feem. Ortho-chlorotoluene txoj kev o-chlorotoluene siv sulfuryl chloride ua tus neeg sawv cev chlorinating los ua cov tshuaj chlorination ntawm 142 ~ 196 ℃. Cov khoom yog 2,4-dichlorotoluene thiab 2,3-dichlorotoluene, thiab unreacted Cov muaj pes tsawg leeg ntawm raw khoom yog 55%, 6%, thiab 39%, feem. Tom qab distillation (2,4-dichlorotoluene bp 200 ° C, 2,3-dichlorotoluene bp 207-208 ° C, o-chlorotoluene bp 157-159 ° C), 2,4-dichlorotoluene raug cais. Ortho-nitrotoluene txoj kev Ortho-nitrotoluene yog chlorinated nyob rau hauv lub xub ntiag ntawm FeCl3 catalyst ntawm 35 ~ 40 ℃. Thaum tus txheeb ze ntom ntom ntawm cov reactant ncav cuag 1.320 (15 ℃), ntxuav cov khoom mus rau nruab nrab, thiab cov reactant muaj 15% ntawm raw khoom, 2-chloro-6-nitrotoluene 49%, 4-chloro-2-nitrotoluene 21% , thiab 15% polychloride, tom qab rectification thiab crystallization kev kho mob, cov tshuaj rau 2-chloro-6-nitrotoluene Cov yields ntawm 4-chloro-2-nitrotoluene thiab 4-chloro-2-nitrotoluene yog 50% thiab 30% feem. 4-chloro-2-nitrotoluene yog tau los ntawm hydrogenation txo cov tshuaj tiv thaiv thiab chav distillation kom tau 4-chloro-2-amino. Toluene, diazotization thiab ntxiv CH2Cl2 rau Sandmeyer cov tshuaj tiv thaiv kom tau 2,4-dichlorotoluene. Cov txheej txheem yog siv los tsim 4-chloro-2-nitrotoluene uas yog cov khoom lag luam ntawm 2-chloro-6-nitrotoluene (siv raws li qhov nruab nrab ntawm cov tshuaj tua kab mob quinclorac). 2,4-Diaminotoluene Txoj Kev 2,4-Diaminotoluene tau txais cov tshuaj tiv thaiv diazotization nyob rau hauv lub xub ntiag ntawm NaNO2 thiab hydrochloric acid, thiab ces ua Sandmeyer cov tshuaj tiv thaiv nyob rau hauv lub xub ntiag ntawm Cu2Cl2 kom tau 2,4-dichlorotoluene. 3-Chloro-4-methylaniline txoj kev 3-chloro-4-methylaniline thiab hydrochloric acid yog ntxiv rau cov tshuaj tiv thaiv kettle, NaNO2 aqueous tov yog ntxiv dropwise ntawm 3 ~ 5 ℃, thiab qhov ntxiv yog tiav nyob rau hauv 2 ~ 3h rau diazotization tom qab lub cov tshuaj tiv thaiv, cov kua diazotized yog ntxiv dropwise rau cov tshuaj hydrochloric acid uas muaj Cu2Cl2 ntawm 2-5 ° C los ua Sandmeyer cov tshuaj tiv thaiv kom tau 2,4-dichlorotoluene. Ntawm cov txheej txheem saum toj no, cov tshuaj chloride tsim los ntawm kev siv p-chlorotoluene thiab o-chlorotoluene ua raw cov ntaub ntawv muaj ntau yam impurities thiab muaj cov ntsiab lus kub zoo sib xws. Nws yog ib qho tsim nyog yuav tsum tau siv cov cuab yeej ua haujlwm siab kom ua tiav kom tau txais ntau dua 98% ntawm 2,4-dichlorotoluene. Ob txoj hauv kev no nyuaj rau kev khiav lag luam, thiab cov cuab yeej siv peev nyiaj yog siab. Txoj kev 2,4-diaminotoluene tsis haum rau industrialization, thiab txoj kev o-nitrotoluene thiab 3-chloro-4-methylaniline txoj kev npaj 2,4-dichlorotoluene muaj tib lub hauv paus ntsiab lus, thiab ob qho tib si yuav tsum tau diazotization thiab Sandmeyer hauv teb. , muaj qhov tsis txaus ntawm cov dej khib nyiab ntau dua. Txoj kev o-nitrotoluene yog siv los sib koom ua 2-chloro-6-nitrotoluene, uas txo qis ntxiv kom tau 2-chloro-6-aminotoluene, uas yog ib qho tseem ceeb nruab nrab ntawm kev tsim cov tshuaj tua kab mob quinclorac.